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Youping Deng, Ph.D.

John J. Chen, Ph.D.

Professor & Lead Bioinformatician

Director of Bioinformatics Core

Office: BSB 325B
(808) 692-1664


  • Ph.D.
    Peking Union Medical College and Chinese Academy of Medical Sciences
    Beijing, China

Research Focus

Bioinformatics, biomedical informatics, cancer, genomics, systems biology

Selected Publications

  • Chen X, Chen H, Dai M, Ai J, Li Y, Mahon B, Dai S, Deng Y. Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions. Oncotarget. 2016 May 2. doi: 10.18632/oncotarget.9124. PubMed PMID: 27153558. [Epub ahead of print]
  • Hu L, Ai J, Long H, Liu W, Wang X, Zuo Y, Li Y, Wu Q, Deng Y. Integrative microRNA and gene profiling data analysis reveals novel biomarkers and mechanisms for lung cancer. Oncotarget. 2016 Feb 23;7(8):8441-54. doi: 10.18632/oncotarget.7264. PubMed PMID: 26870998; PubMed Central PMCID: PMC480978.
  • Wang C, Gong B, Buschel PR, Thierry-Mieg J, Thierry-Mieg D, Xu J, Fang H, Hong H, Shen J, Su Z, Meehan J, Li X, Yang L, Li H, Labaj PP, Kreil DP, Megherbi D, Gaj S, Caiment F, van Delft J, Kleinjans J, Scherer A, Devanarayan V, Wang J, Yang Y, Qian HR, Lancashire LJ, Bessarabova M, Nikolsky Y, Furlanello C, Chierici M, Albanese D, Jurman G, Riccadonna S, Filosi M, Visintainer R, Zhang KK, Li J, Hseih JH, Svolboda DL, Fuscoe JC, Deng Y, Shi L, Paules R Auerbach SS, Tong W. The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance. Nat Biotechnol. 2014 Sep; 32(9):926-32. doi: 10.1038/nbt.3001. Epub 2014 Aug 24. PubMed PMID: 25150839; PubMed Central PMCID: PMC4243706.
  • Melson J, Li Y, Cassinotti E, Melnikov A, Boni L, Ai J, Greenspan M, Mobarhan S, Levenson V, Deng Y. Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer. Int J Cancer. 2014 Jun 1;134(11): 2656-62. doi: 10.1002/ijc.28593. Epub 2013 Nov 29. PubMed PMID: 224288256.
  • Pirooznia M, Habib T, Perkins EJ, Deng Y. GOfetcher: a database with complex searching facility for gene ontolog. Bioinformatics. 2008 Nov 1;24(21):2561-3. doi:10.1093/bioinformatics/btn441. Epub 2008 Aug 26. PubMed PMID: 18728045.

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